Depression is a potentially serious debilitating condition that significantly impacts the way people function and participate in daily activities. Symptoms of depression include feeling sad, helpless, hopeless, worthless or guilty. The person may have little energy and feel like sleeping all the time, or may experience insomnia and get very little sleep. Appetite may increase or decrease causing weight gain, or loss. People with depression often report little interest or pleasure in doing things including activities of daily living such as bathing. Some people have thoughts of suicide and self harm.